Research programmes and clinical trials

The Department of Neurosurgery has several active research programmes with national and international collaborators.

The Brain Tumour Research group has active research interests in multi-modal imaging, glioma growth and metastatic disease. They have collaborations with basic scientist at The University of Liverpool and University of Wolverhampton, as well as being members of Brain Tumour North West (BTNW) and the Liverpool Neuro-oncology Research Group (LNRG).

The hydrocephalus and CSF disorders clinicians have been awarded a £2.1million grant from the National Institute for Health Research (NIHR) to conduct a national multi-centre clinical trial. 

The British Antibiotic And Silver Impregnated Catheters for ventriculoperitoenal Shunts multi-centre randomised controlled trials (The BASICS trial) will investigate whether silver or antibiotic impregnated catheters can reduce the incidence of infection in newly inserted shunts in patients with hydrocephalus. Mr Michael Jenkinson is the co-chief investigator.

Mr Martin Wilby has an active research interest in brain injury and is the principle investigator for the RescuICP trial.  In collaboration with the pain physicians he has applied for funding for the NERVES trial, which will investigate whether nerve root injection is superior to lumbar microdiscectomy for acute sciatica.

The spinal surgeons have established SPINE TANGO, which is used to derive data on patient reported outcome measures (PROMs). This service is being led by Mr Tim Pigott.

Mr Paul Eldridge is the prinicple investigator for several neurovascular clinical trials for patients with subarachnoid haemorrhage and AVMs.

The Walton Centre has an active Clinical Trials Unit and several clinical trials are open to patients with a variety of clinical conditions: