COVID-19 restrictions to remain in place at The Walton Centre

Restrictions remain in place across the NHS in relation to the COVID-19 pandemic. The safety measures in place over the 18 months therefore remain in place at The Walton Centre - and in our other clinic settings within the community – until further notice.

Due to the increased transmission risk posed by the Omicron variant, visiting has been suspended within The Walton Centre except for exceptional circumstances.

Diagnostic tests

The following tests are performed by the Neuropathology Team. Please see below for sample requirements, test costs, and target turnaround times from sample receipt. The team will endeavour to accommodate shorter turnaround times in clinically urgent cases. Please contact the laboratory to discuss this prior to sending the sample.

Routine biopsies

Assay information 
Neuropathology offer both technical work up and reporting of specialist central nervous system biopsies.

Specimen type(s) and minimum volume 
Tissue fixed in formalin, paraffin embedded blocks or pre-prepared slides.

Cost 
Dependant on complexity, please contact the laboratory for more information.

Transport 
Specialist courier (formalin fixed tissue)
Sample must arrive within working hours Monday - Friday, 9am- 5pm.
First class post (blocks/slides)

Turnaround time 
5 -7 working days

Accredited assay 
UKAS 8642

External Quality Assurance (EQA) 
• UK NEQAS CPT – Neuropathology
• UK NEQAS for IHC & FISH

Further information 
email: wcf-tr.wcftpathologylabs@nhs.net 
Telephone: 0151 5564002

 

Immunohistochemistry

Assay information 
Neuropathology offer a comprehensive repertoire of specialist immunohistochemistry antibodies performed using the Roche Benchmark Ultra. Please contact the laboratory for our current repertoire of antibodies or refer to our UKAS scope.

Specimen type(s) and minimum volume 
Paraffin embedded tissue blocks or pre-cut slides.

Cost 
£20 per slide

Transport 
First class post (blocks/slides)

Turnaround time 
Three working days

Accredited assay 
UKAS 8642

External Quality Assurance (EQA) 
• UK NEQAS CPT – Neuropathology
• UK NEQAS for IHC & FISH

Further information 
email: wcf-tr.wcftpathologylabs@nhs.net 
Telephone: 0151 5564002

 

Special stains

Assay information 
Neuropathology offer a comprehensive repertoire of specialist tinctorial stains. Please contact the laboratory for our current repertoire or refer to our UKAS scope.

Specimen type(s) and minimum volume 
Paraffin embedded tissue blocks or pre-cut slides.

Cost 
£10 per slide

Transport 
First class post (blocks/slides)

Turnaround time 
Three working days

Accredited assay 
UKAS 8642

External Quality Assurance (EQA) 
• UK NEQAS CPT – Neuropathology

Further information 
email: wcf-tr.wcftpathologylabs@nhs.net 
Telephone: 0151 5564002

 

Muscle enzyme histochemistry

Assay information 

Neuropathology offer a full muscle enzyme histochemistry work up including technical work and full interpretive reporting.

Specimen type(s) and minimum volume
Fresh muscle biopsy measuring minimum of 1cm3 wrapped in saline soaked gauze

Cost
£450 for both technical work and report

Transport
Specialist courier. Sample must arrive within working hours Monday-Friday, 9am- 3pm.

Turnaround time
15 working days

Accredited assay
UKAS 8642

External Quality Assurance (EQA)
• UK NEQAS Muscle Histochemistry

Further information
email: wcf-tr.wcftpathologylabs@nhs.net 
Telephone: 0151 5564002

Please contact the laboratory to ensure we are able to accept your muscle biopsy prior to sending.

 

Muscle inflammatory panel

Assay information
Neuropathology offers a comprehensive muscle inflammatory immunohistochemistry panel including technical work and full interpretive reporting.


Specimen type(s) and minimum volume
Fresh muscle biopsy measuring minimum of 1cm3 wrapped in saline soaked gauze.

Cost
£80 for both technical work and report

Transport
Specialist courier. Sample must arrive within working hours Monday-Friday, 9am- 3pm.

Turnaround time
15 working days

Accredited assay
UKAS 8642

External Quality Assurance (EQA) 
N/A

Further information
email: wcf-tr.wcftpathologylabs@nhs.net 
Telephone: 0151 5564002

Please contact the laboratory to ensure we are able to accept your muscle biopsy prior to sending.

 

Muscular dystrophy panel

Assay information
Neuropathology offer a full muscular dystrophy immunohistochemistry work up including technical work and full interpretive reporting.


Specimen type(s) and minimum volume
Fresh muscle biopsy measuring minimum of 1cm3 wrapped in saline soaked gauze

Cost
£150 for both technical work and report

Transport
Specialist courier. Sample must arrive within working hours Monday-Friday, 9am- 3pm.

Turnaround time
15 working days

Accredited assay
UKAS 8642

External Quality Assurance (EQA)
N/A

Further Information
email: wcf-tr.wcftpathologylabs@nhs.net 
Telephone: 0151 5564002

Please contact the laboratory to ensure we are able to accept your muscle biopsy prior to sending.

 

Peripheral nerve biopsies

Assay information
Neuropathology offer both technical work up and reporting of peripheral nerve biopsies.

Specimen type(s) and minimum volume
Approx. 3cm of nerve biopsy. Please contact the laboratory prior to taking the nerve biopsy so we can provide you with a protocol and the appropriate fixatives.

Cost
Please contact the laboratory.

Transport
Specialist courier. Sample must arrive within working hours Monday-Friday, 9am- 3pm.

Turnaround time
15 working days

Accredited Assay
UKAS 8642

External Quality Assurance (EQA)
N/A

Further Information
email: wcf-tr.wcftpathologylabs@nhs.net 
Telephone: 0151 5564002

Please contact the laboratory to ensure we are able to accept your nerve biopsy prior to sending.

 

Transmission electron microscopy

Assay information
Neuropathology offer specimen processing (up to four blocks) / Electron microscopy preparation and ultrastructure report on appropriate central nervous system tissue.

Specimen type(s) and minimum volume
Please contact the laboratory to discuss specimen type and requirements

Cost
£250

Transport
Specialist courier. Sample must arrive within working hours, Monday – Friday 9am-5pm.

Turnaround time
15 working days

Accredited assay
UKAS 8642

External Quality Assurance (EQA)
UKNEQAS for Electron Microscopy

Further information
email: wcf-tr.wcftpathologylabs@nhs.net 
Telephone: 0151 5564002

Please contact the laboratory to ensure we are able to accept your sample prior to sending.

 

Second opinions

Please contact the laboratory for more information

 

CSF cytology

Assay information 

Neuropathology provides CSF cytology reporting primarily for the detection of malignant cells

Specimen type(s) and minimum volume
CSF fluid pre-fixed in 10% alcoholic formalin or if sending fresh, please ensure it arrives the same day.

Cost
£30 for both technical work and reporting

Transport
Specialist courier. Sample must arrive within working hours Monday-Friday, 9am- 5pm.

Turnaround time
Three working days 

Accredited assay
UKAS 8642

External Quality Assurance (EQA)
N/A

Further information
email: wcf-tr.wcftpathologylabs@nhs.net 
Telephone: 0151 5564002

Please contact the laboratory to ensure we are able to accept your sample prior to sending.

 

 

 

 

 

Page last updated: 22 September 2021